Histopathological characteristics of interstitial cystitis/bladder pain syndrome without Hunner lesion.

Aram KimJu-Young HanChae-Min RyuHwan Yeul YuSeungun LeeYongHwan KimSe Un JeongYoung Mee ChoDong-Myung ShinMyung-Soo Choo

Published in: Histopathology (2017)

Non-Hunner-type IC is characterized by severe fibrosis and increased mast cell infiltration, whereas Hunner-type IC is characterized by severe inflammation and urothelial denudation in the entire bladder. Fibrosis in the bladder of IC/BPS patients was correlated with increased urinary frequency and decreased bladder capacity.

Keyphrases

urinary tract
spinal cord injury
end stage renal disease
ejection fraction
newly diagnosed
early onset
chronic kidney disease
oxidative stress
prognostic factors
peritoneal dialysis
high grade