Primary aldosteronism is associated with decreased low-density and high-density lipoprotein particle concentrations and increased GlycA, a pro-inflammatory glycoprotein biomarker.
Annika M A BerendsEdward BuitenwerfEke G GruppenWim J SluiterStephan J L BakkerMargery A ConnellyMichiel N KerstensRobin P F DullaartPublished in: Clinical endocrinology (2018)
Primary aldosteronism is associated with lower concentrations of LDL and HDL particles and to some extent also with lower TG and TRL particle concentrations. PA is also characterized by increased GlycA levels, indicating enhanced low-grade chronic inflammation. Low HDL particle concentrations and increased GlycA could contribute to accelerated cardiovascular disease development in PA.