The effect of normal, metaplastic, and neoplastic esophageal extracellular matrix upon macrophage activation.
Lindsey T SaldinMolly KlimakRyan C HillMadeline C CramerLuai HuleihelXue LiMaria Quidgley-MartinDavid CardenasTimothy J KeaneRicardo LondonoGeorge HusseyLori KellyJuliann E KosovecEmily J LloydAshten N OmsteadLi ZhangAlejandro NieponiceBlair JobeKirk HansenAli H ZaidiStephen F BadylakPublished in: Journal of immunology and regenerative medicine (2020)
A progressively diseased ECM, as exists within the esophagus exposed to chronic gastric reflux, can provide insights into novel biomarkers of early disease and identify potential therapeutic targets.