Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study.

Yuwei HeXiaomei XueRobert TerkeltaubNicola DalbethTony R MerrimanDavid B MountZhe FengXinde LiLingling CuiZhen LiuYan XuYing ChenHailong LiAichang JiXiaopeng JiXuefeng WangJie LuChanggui Li

Published in: Arthritis research & therapy (2022)

Approximately half of gout subjects had acidic urine pH. Urine pH < 5.0 was associated with significantly increased nephrolithiasis, renal cyst, microhematuria, and proteinuria. The results support prospective clinical investigation of urinary alkalinization in selected gout patients with acidic urine pH.

Keyphrases

uric acid
end stage renal disease
ionic liquid
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
metabolic syndrome