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Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients.

Laurence GentonMenno PruijmDaniel TetaIsabelle BassiPatrice D CaniNadia GaïaFrançois R HerrmannNicola MarangonJulie MareschalGiulio G MuccioliCatherine StoermannFrancesco SurianoArlene Wurzner-GhajarzadehVladimir LazarevicJacques Schrenzel
Published in: Journal of cachexia, sarcopenia and muscle (2021)
The BCAA and glycine supplementations had no impact on the serum levels of cytokines, appetite mediators, intestinal permeability, endocannabinoids, or faecal IgA. Overall faecal microbiota composition and microbial diversity did not change with the glycine or BCAA supplementation but decreased the abundance of L. paracasei and B. dentium.
Keyphrases
  • end stage renal disease
  • chronic kidney disease
  • amino acid
  • ejection fraction
  • newly diagnosed
  • microbial community
  • prognostic factors
  • weight loss
  • endothelial cells
  • patient reported
  • antibiotic resistance genes