Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients.

Laurence GentonMenno PruijmDaniel TetaIsabelle BassiPatrice D CaniNadia GaïaFrançois R HerrmannNicola MarangonJulie MareschalGiulio G MuccioliCatherine StoermannFrancesco SurianoArlene Wurzner-GhajarzadehVladimir LazarevicJacques Schrenzel

Published in: Journal of cachexia, sarcopenia and muscle (2021)

The BCAA and glycine supplementations had no impact on the serum levels of cytokines, appetite mediators, intestinal permeability, endocannabinoids, or faecal IgA. Overall faecal microbiota composition and microbial diversity did not change with the glycine or BCAA supplementation but decreased the abundance of L. paracasei and B. dentium.

Keyphrases

end stage renal disease
chronic kidney disease
amino acid
ejection fraction
newly diagnosed
microbial community
prognostic factors
weight loss
endothelial cells
patient reported
antibiotic resistance genes