An Effective Synthesis of Previously Unknown 7-Aryl Substituted Paullones.
Dmitrii A AksenovAlesia S AkulovaElena A AleksandrovaNicolai A AksenovAlexander V LeontievAlexander V AksenovPublished in: Molecules (Basel, Switzerland) (2023)
A straightforward three-step procedure affording a wide range of novel 7-aryl substituted paullone derivatives was developed. This scaffold is structurally similar to 2-(1 H -indol-3-yl)acetamides-promising antitumor agents-hence, could be useful for the development of a new class of anticancer drugs.