Impact of Subthalamic Deep Brain Stimulation on Impulse Control Disorders in Parkinson's Disease: A Prospective Study.
Marie des Neiges SantinPaul VoulleminotAgathe VrillonElodie HainqueMatthieu BereauOuhaid Lagha-BoukbizaThomas WirthSolveig MontautEric BardinetMaeva KyhengAnne-Sophie RollandJimmy VoirinSophie DrapierFranck DurifAlexandre EusebioCaroline GiordanaNicolas AuzouJean-Luc HouetoCécile HubschBéchir JarrayaChloé LaurencinDavid MalteteMylène MeyerOlivier RascolTiphaine RouaudMélissa TirCaroline MoreauJean-Christophe CorvolFrançois ProustDavid GrabliDavid DevosChristine TranchantMathieu Anheimnull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
This 1-year, postoperative follow-up study showed ICD regression and dopaminergic drug reduction with optimal position of the active contacts within the subthalamic nucleus. Whereas patients with PD with preoperative ICD were prone to postoperative apathy, we also showed that those with preoperative apathy had a higher risk to experience postoperative de novo ICD, further highlighting the meaningful influence of postoperative management of dopaminergic medication on outcome and the continuum between apathy and ICD. © 2020 International Parkinson and Movement Disorder Society.