Identifying and predicting longitudinal trajectories of care for people newly diagnosed with HIV in South Africa.
Laura PlattAi XuJanet GiddyLaura M BogartAndrew BoulleRobert A ParkerElena LosinaIngrid V BassettPublished in: PloS one (2020)
One-fifth of people newly-diagnosed with HIV presented with low CD4 counts that failed to rise over time. Less than 40% were in a trajectory characterized by increasing CD4 counts. Patients in more favorable trajectories were younger, less likely to have TB, and less likely to report barriers to healthcare. Better understanding barriers to early care engagement and ART initiation will be necessary to improve long-term clinical outcomes.
Keyphrases
- newly diagnosed
- healthcare
- hiv positive
- antiretroviral therapy
- hiv infected
- south africa
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- men who have sex with men
- hiv aids
- depressive symptoms
- quality improvement
- end stage renal disease
- mycobacterium tuberculosis
- chronic kidney disease
- pain management
- ejection fraction
- peritoneal dialysis
- patient reported outcomes
- prognostic factors