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Survival and clinical outcomes of patients with melanoma brain metastasis in the era of checkpoint inhibitors and targeted therapies.

Elham VosoughiJee Min LeeJames R MillerMehdi NosratiDavid R MinorRoy AbendrothJohn W LeeBrian T AndrewsLewis Z LengMax WuStanley P LeongMohammed Kashani-SabetKevin B Kim
Published in: BMC cancer (2018)
These results show a significant improvement in the overall survival of patients with melanoma brain metastasis in the era of novel therapies. In addition, they suggest the activity of anti-PD-1 therapy specifically in the setting of brain metastasis.
Keyphrases
  • resting state
  • white matter
  • functional connectivity
  • cerebral ischemia
  • free survival
  • multiple sclerosis
  • stem cells
  • cell cycle
  • oxidative stress
  • cell proliferation
  • bone marrow
  • replacement therapy