EUS-guided fine needle biopsy of an anal gland adenocarcinoma with submucosal rectal invasion after normal colonoscopy. An uncommon histology.
Esteban Fuentes-ValenzuelaFernando LabargaBeatriz Madrigal RubialesVicente SimóCarlos de la Serna HigueraPublished in: Revista espanola de enfermedades digestivas (2023)
We present the case of a 63-year-old male with long-term anal pain. A pelvic MRI was performed showing a tumor arising from the intersphincteric extending into the submucosal layer of the posterior rectal wall. The image was compatible with a cT4N0 ano-rectal carcinoma without any distant metastasis on the CT scan. Histopathology showed neoplastic proliferation cells arranged in nodules and nidus consistent with anal glands adenocarcinoma with a positive immunohistostaining for CK7 and MUC5+ .
Keyphrases
- rectal cancer
- locally advanced
- contrast enhanced
- computed tomography
- dual energy
- high grade
- image quality
- ultrasound guided
- induced apoptosis
- magnetic resonance imaging
- fine needle aspiration
- squamous cell carcinoma
- chronic pain
- signaling pathway
- positron emission tomography
- cell cycle arrest
- pain management
- magnetic resonance
- lymph node
- air pollution
- deep learning
- cell migration
- endoplasmic reticulum stress
- protein kinase
- cell death
- radiation therapy
- cell proliferation
- machine learning
- endoscopic submucosal dissection