Utility of SARS-CoV-2 Subgenomic RNA in Kidney Transplant Recipients Receiving Remdesivir.
Genoveva CuestaJudit CachoDavid CucchiariSabina HerreraAbiu SempereTabassum AkterAnna VillasanteMiriam GarridoFrederic CofanFritz DiekmannAlex SorianoMaria Angeles MarcosMarta BodroPublished in: Infectious diseases and therapy (2024)
Based on these data, we hypothesize that sgRNA may have clinical utility to help monitor virologic response more accurately than gRNA in KTR who receive remdesivir. Moreover, patients with negative sgRNA at baseline may not require antiviral treatment and others presenting positive sgRNA at day 5 could benefit from prolonged or combined therapies.