Association between CKD-MBD biomarkers and symptom burden in older patients with advanced CKD: Results from the EQUAL study.

Lorenza Magagnoli Mario Gennaro Cozzolino Marie Evans Fergus John Caskey Friedo W Dekker Claudia Torino Maciej Szymczak Christiane Drechsler Maria PippiasAntonio VilasiRoemer J Janse Magdalena Krajewska Vianda S Stel Kitty J Jager Nicholas C Chesnayenull null

Published in: Clinical journal of the American Society of Nephrology : CJASN (2024)

In older patients with advanced CKD not on dialysis, mild-to-moderately increased PTH was associated with a lower symptom burden, although the effect size was relatively small (less than one symptom). Neither phosphate nor calcium were associated with the overall symptom burden, except for the combination of severe hyperphosphatemia and severe hyperparathyroidism which was associated with an increased number of symptoms.

Keyphrases

chronic kidney disease
end stage renal disease
patient reported
physical activity
early onset
middle aged
depressive symptoms
drug induced
peritoneal dialysis