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Angiotensin II upregulates endothelin receptors through the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway in vascular smooth muscle cells.

Xin ZhangHongmei ZhangXinpu YangQiaohong QinXia SunYing HouDi ChenMin JiaXingli SuYulong Chen
Published in: The Journal of pharmacy and pharmacology (2022)
Ang II upregulated ET receptors in VSMCs to elevate BP by inhibiting AMPK, thereby inhibiting Sirt1.
Keyphrases
  • vascular smooth muscle cells
  • angiotensin ii
  • protein kinase
  • angiotensin converting enzyme
  • signaling pathway
  • ischemia reperfusion injury