Green coffee methanolic extract and silymarin protect against CCl4-induced hepatotoxicity in albino male rats.

Haddad A El RabeySamar M RezkMohamed I SakranGhena M MohammedOmar BahattabMaha J BalgoonMohamed A ElbakryNadia Bakry

Published in: BMC complementary medicine and therapies (2021)

Green coffee methanolic extract, silymarin, and their combination succeeded in protecting the male rats against CCl4 hepatotoxicity due to their antioxidant activity. Effect of green coffee methanolic extract mixed with silymarin in G5 was more efficient than that of green coffee methanolic extract in G3 or silymarin in G4.

Keyphrases

drug induced
oxidative stress
liver injury
anti inflammatory
high glucose
endothelial cells
stress induced