Impact of transforming growth factor beta 1 on normal and thyroid cancer side population cells.

Nani Md LatarKamilla MahkamovaJoanna ElsonIsha KarnikRachel SutherlandSebastian AspinallAnnette Meeson

Published in: Endocrine (2022)

TGF-β1 exposure transiently regulates thyroid cancer SP cells, leading to a reduction in SP percentages, while withdrawal of TGF-β1 results in restoration of the SP phenotype.

Keyphrases

transforming growth factor
induced apoptosis
epithelial mesenchymal transition
cell cycle arrest
cell death
pi k akt