Management of Oral Anticoagulation and Antiplatelet Therapy in Post-Myocardial Infarction Patients with Acute Ischemic Stroke with and without Atrial Fibrillation.
Francesca Romana PezzellaMarilena MangiardiMario FerranteSebastiano FabianoSabrina AnticoliFabrizio Giorgio PennacchiAntonella UrsoLeonardo De LucaValeria CasoPublished in: Journal of clinical medicine (2022)
The association between atrial fibrillation (AF), acute coronary syndrome (ACS), and stroke is a complex scenario in which the assessment of both thrombotic and hemorrhagic risk is necessary for scheduling an individually tailored therapeutic plan. Recent clinical trials investigating new antithrombotic drugs and dual and triple pathways in high-risk cardiovascular patients have revealed a new therapeutic scenario. In this paper, we review the burden of ischemic stroke (IS) in patients post-myocardial infarction with and without atrial fibrillation and the possible therapeutic strategies from a stroke point of view.
Keyphrases
- atrial fibrillation
- acute coronary syndrome
- antiplatelet therapy
- percutaneous coronary intervention
- oral anticoagulants
- catheter ablation
- heart failure
- left atrial
- clinical trial
- direct oral anticoagulants
- left atrial appendage
- end stage renal disease
- acute ischemic stroke
- ejection fraction
- chronic kidney disease
- prognostic factors
- coronary artery disease
- brain injury
- blood brain barrier
- subarachnoid hemorrhage
- open label