A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication.

William R TaylorJonathan P StoyeIan A Taylor

Published in: BMC structural biology (2017)

These results indicate that, as well as the duplication of the double domain capsid, there may have been an even more ancient gene-duplication that preceded the double domain structure. In addition, our structure comparison methodology demonstrates a general approach to problems where the components have a high intrinsic level of similarity.

Keyphrases

mental health
high resolution
copy number
gene expression
transcription factor
clinical evaluation