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Randomised clinical trial: faecal microbiota transplantation for recurrent Clostridum difficile infection - fresh, or frozen, or lyophilised microbiota from a small pool of healthy donors delivered by colonoscopy.

Z D JiangN J AjamiJ F PetrosinoG JunC L HanisM ShahL HochmanV Ankoma-SeyA W DuPontM C WongA AlexanderS KeHerbert L DuPont
Published in: Alimentary pharmacology & therapeutics (2017)
Comparative efficacy in faecal microbiota transplantation was observed in subjects receiving fresh or frozen faecal product from the same donors. The lyophilised product had a slightly lowered efficacy compared with fresh product, but it resembled other treatments in microbial restoration 1 month after faecal microbiota transplantation.
Keyphrases
  • clinical trial
  • open label
  • cell therapy
  • study protocol
  • phase ii
  • kidney transplantation
  • bone marrow