Login / Signup

Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4.

Fengtian SunYuntong SunJunyan ZhuXiaoling WangCheng JiJiahui ZhangShenyuan ChenYifan YuWenrong XuWenrong Xu
Published in: Stem cell research & therapy (2022)
Our findings indicated that MSC-sEV ameliorated DR through NEDD4-induced regulation on PTEN/AKT/NRF2 signaling pathway, thus revealing the efficiency and mechanism of MSC-sEV-based retinal protection and providing new insights into the treatment of DR.
Keyphrases