Microvascular Network Remodeling in the Ischemic Mouse Brain Defined by Light Sheet Microscopy.
Nina HagemannYachao QiAyan Mohamud YusufAnRan LiAnthony SquireTobias TertelBernd GiebelPeter LudewigPhilippa SpangenbergJianxu ChenAxel MosigMatthias GunzerJanine GronewoldPublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
Utilizing light sheet microscopy together with automated image analysis, we characterized microvascular remodeling post-ischemia in unprecedented detail. This technology will significantly advance our understanding of microvascular restorative processes and pave the way for novel treatment developments in the stroke field.