Cerebral arteriolosclerosis, lacunar infarcts, and cognition in older Black adults.

Debra A FleischmanKonstantinos ArfanakisSue E LeurgansZoe ArvanitakisMelissa LamarS Duke HanVictoria N PooleDavid A BennettLisa L Barnes

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Older Black adults are at risk of cerebral small vessel disease (CSVD) and dementia. Examined magnetic resonance imaging-derived measure of arteriolosclerosis (ARTS), infarcts, and cognition. ARTS load was widely associated with lower cognition after adjusting for infarct load. Infarct load was specifically associated with lower complex attention. More within-Black in vivo studies of CSVD subtypes and cognition are needed.

Keyphrases

mild cognitive impairment
magnetic resonance imaging
white matter
subarachnoid hemorrhage
physical activity
community dwelling
middle aged
cognitive impairment
acute coronary syndrome
heart failure
coronary artery disease
percutaneous coronary intervention