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From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function.

Maaike M De VriesDiana A van der PlaatIvana NedeljkovicRikst Nynke Verkaik-SchakelWierd KooistraNajaf AminCornelia M van DuijnCorry-Anke BrandsmaCleo C van DiemenJudith M VonkH Marike Boezen
Published in: Respiratory research (2018)
This study is the first to validate a panel of CpG-sites that are associated with cigarette smoking and lung function levels in whole blood in the tissue of interest: lung tissue.
Keyphrases
  • lung function
  • dna methylation
  • cystic fibrosis
  • chronic obstructive pulmonary disease
  • air pollution