Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations.
James J HobsonPaul CurleyAlison C SavageAmer Al-KhoujaMarco SiccardiCharles FlexnerCaren Freel MeyersAndrew OwenSteven P RannardPublished in: Nanoscale advances (2019)
The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.
Keyphrases
- drug release
- water soluble
- antiretroviral therapy
- hiv infected
- drug delivery
- hyaluronic acid
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- hiv positive
- tissue engineering
- quantum dots
- ionic liquid
- case control
- highly efficient
- reduced graphene oxide
- molecularly imprinted
- mass spectrometry
- high resolution
- walled carbon nanotubes
- electronic health record