Transplantation of Heat-Shock Preconditioned Neural Stem/Progenitor Cells Combined with RGD-Functionalised Hydrogel Promotes Spinal Cord Functional Recovery in a Rat Hemi-Transection Model.

Published in: Stem cell reviews and reports (2023)

The surgical removal of the glial scar in combination with HS-preconditioning and RGD-functionalised hydrogels should be considered as a new paradigm in NSPC transplantation for spinal cord regeneration treatment.

Keyphrases

spinal cord
heat shock
wound healing
neuropathic pain
drug delivery
spinal cord injury
stem cells
hyaluronic acid
heat stress
oxidative stress
heat shock protein
cell therapy
tissue engineering
drug release
mesenchymal stem cells