Focal to Bilateral Tonic-Clonic Seizures Predict Pharmacoresistance in Focal Cortical Dysplasia-Related Epilepsy.

Phat ChangHua XieVenkata Sita Priyanka IllapaniXiaozhen YouTayyba AnwarArchana PasupuletiThuy-Anh VuL Gilbert VezinaTaha GholipourChima O OluigboAnqing ZhangWilliam Davis Gaillard Nathan T Cohen

Published in: Epilepsia (2023)

In a heterogeneous population of surgical and non-operated patients with FCD-related epilepsy, the presence of FTBTC seizures is associated with a tremendous risk of PRE. This finding is a recognizable marker to help neurologists identify those children with FCD-related epilepsy at high risk of PRE, and can flag patients for earlier consideration of potentially curative surgery. FCD dominant network also contributes to FTBTC seizure clinical expression.

Keyphrases

temporal lobe epilepsy
end stage renal disease
minimally invasive
prognostic factors
ejection fraction
newly diagnosed
chronic kidney disease
young adults
long non coding rna
peritoneal dialysis
binding protein
case report
patient reported outcomes