Evolution of the Plasmodium vivax multidrug resistance 1 gene in the Greater Mekong Subregion during malaria elimination.

Huguette Gaelle Ngassa MbendaMeilian WangJian GuoFaiza Amber SiddiquiYue HuZhaoqing YangVeerayuth KittichaiJetsumon SattabongkotYaming CaoLubin JiangLiwang Cui

Published in: Parasites & vectors (2020)

This study showed that P. vivax populations in the China-Myanmar border has experienced major changes in the Pvmdr1 residues proposed to be associated with chloroquine resistance, suggesting that drug selection may play an important role in the evolution of this gene in the parasite populations.

Keyphrases

plasmodium falciparum
copy number
genome wide
genome wide identification
genetic diversity
gene expression
emergency department
life cycle