Intraoperative metabolic changes associated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Jesús David Rubio-LópezManuel Durán-MartínezAndrea Moreno-BlázquezLidia Rodríguez-OrtizBlanca Rufián-AndújarFrancisca Valenzuela-MolinaÁngela Casado AdamJuan M Sánchez-HidalgoSebastián Rufián-PeñaAntonio Romero-RuizJ Briceño-DelgadoArjona-Sánchez ÁlvaroPublished in: Langenbeck's archives of surgery (2023)
The administration of HIPEC after CRS causes significant changes in internal homeostasis. Although the closed technique causes a greater increase in temperature, it is not related to higher morbidity rates. The patient's age, post-HIPEC potassium level, and pre-HIPEC glycemia are predictive factors for morbidity.