Effect of leukoreduction on transfusion-related immunomodulation in patients undergoing cardiac surgery.
Atif Irfan KhanGopal Kumar PatidarR LakshmyNeeti MakhijaSachin TalwarAnjali HazarikaPublished in: Transfusion medicine (Oxford, England) (2020)
Depletion of leukocytes decreased Transfusion Related Immunomodulation (TRIM) effects in patients undergoing cardiac surgery, but this also depends on the degree of leukoreduction. As found in our study, leukofiltration is more effective compared to buffy-coat depletion only.