Impact of the M184V/I Mutation on the Efficacy of Abacavir/Lamivudine/Dolutegravir Therapy in HIV Treatment-Experienced Patients.
Flaminia OlearoHuyen NguyenFabrice BonnetSabine YerlyGilles WandelerMarcel StoeckleMatthias CavassiniAlexandra ScherrerDominique CostagiolaPatrick SchmidHuldrych F GünthardEnos BernasconiJürg BoeniAntonella D'arminio MonforteMaurizio ZazziBarbara RossettiDidier NeauPantxika BellecaveBart RijndersPeter ReissFerdinand WitRoger KouyosAlexandra CalmyPublished in: Open forum infectious diseases (2019)
In ART-experienced patients switching to an abacavir/lamivudine/dolutegravir treatment, we observed few VFs and found no evidence for an impact of previously-acquired M184V/I mutation on this outcome. Additional analyses are required to demonstrate whether these findings will remain robust during a longer follow-up.