Analysis of risk factors for pulmonary tuberculosis with persistent severe inflammation: An observational study.
Masafumi ShimodaTakashi YoshiyamaMasao OkumuraYoshiaki TanakaKozo MorimotoHiroyuki KokutouTakeshi OsawaKoji FuruuchiKeiji FujiwaraKoki ItoKozo YoshimoriKen OhtaPublished in: Medicine (2022)
This study showed that 27.2% of patients who had high or moderate inflammation on admission did not achieve low CRP levels within 4 weeks after admission. Risk factors for persistent severe inflammation in patients with TB were presence of a large cavity (cavity diameter ≥4 cm) on chest CT and a high CRP level on admission. Therefore, in a patient with a large cavity on chest CT and/or CRP ≥9.0 mg/dL on admission, long-term inflammation may occur despite antituberculous therapy if other diseases are ruled out.