Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis.

Anuradha RajamanickamSaravanan MunisankarChandrakumar DollaPradeep A MenonKannan ThiruvengadamThomas B NutmanSubash Babu

Published in: PLoS neglected tropical diseases (2020)

Thus, helminth infections alleviate and anthelmintic therapy partially restores the plasma cytokine and chemokine levels in helminth-diabetes co-morbidity. Our data therefore offer a plausible biological mechanism for the protective effect of helminth infections against T2DM.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
electronic health record
stem cells
big data
metabolic syndrome
insulin resistance
smoking cessation
weight loss
replacement therapy