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BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.

Esther H LipsAnne Benard-SlagterMark OpdamCaroline E ScheermanJelle WesselingFrans B L HogervorstSabine C LinnSuvi SavolaPetra M Nederlof
Published in: Breast cancer research : BCR (2020)
The digitalMLPA is a reliable method to detect a BRCA1- and BRCA2-like pattern on clinical samples and predicts platinum-based chemotherapy benefit in both triple-negative and luminal-type BC.
Keyphrases
  • locally advanced
  • breast cancer risk
  • single cell
  • squamous cell carcinoma
  • chemotherapy induced