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Influence network model uncovers relations between biological processes and mutational signatures.

Bayarbaatar AmgalanDamian WojtowiczYoo-Ah KimTeresa M Przytycka
Published in: Genome medicine (2023)
GENESIGNET provides a new and powerful method to reveal the relation between mutational signatures and gene expression. The GENESIGNET method was implemented in python, and installable package, source codes and the data sets used for and generated during this study are available at the Github site https://github.com/ncbi/GeneSigNet.
Keyphrases
  • gene expression
  • genome wide
  • dna methylation
  • electronic health record
  • big data
  • single cell
  • machine learning
  • deep learning