Transient window of resilience during early development minimizes teratogenic effects of heat in zebrafish embryos.
Triveni MenonSreelaja NairPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2018)
The existence of heat resilient developmental windows and reduced heat teratogenicity during these windows could be an effective step forward in practical application of transient heat for experimental manipulation of ploidy in zebrafish. More broadly, heat resilience before zygotic genome activation suggests that metazoan embryos may possess innate protective features against heat beyond the canonical heat shock response. Developmental Dynamics 247:992-1004, 2018. © 2018 Wiley Periodicals, Inc.