Optimised tissue clearing minimises distortion and destruction during tissue delipidation.

Krit LeeHei Ming LaiMaja Hoejvang SoerensenEdward Sai-Kam HuiVictor Wan-San MaWilliam Chi-Shing ChoYuen-Shan HoRaymond Chuen-Chung Chang

Published in: Neuropathology and applied neurobiology (2020)

Combining the RI-matching solution OPTIClear with detergents, Accu-OptiClearing, can avoid excessive delipidation, leading to accelerated tissue clearing, less tissue damage and better preserved antigens.

Keyphrases

oxidative stress
immune response
weight gain