Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC.

Subreen A KhatibLichun MaHien DangMarshonna ForguesJoon-Yong ChungKris YlayaStephen M HewittJittporn ChaisaingmongkolMathuros RucchirawatXin Wei Wang

Published in: Hepatology (Baltimore, Md.) (2022)

These results are consistent with the hypothesis that increased apoptotic cell death may lead to greater tumor heterogeneity and thus worse patient outcomes.

Keyphrases

cell death
single cell
cell cycle arrest
rna seq
high throughput
anti inflammatory