Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC.
Subreen A KhatibLichun MaHien DangMarshonna ForguesJoon-Yong ChungKris YlayaStephen M HewittJittporn ChaisaingmongkolMathuros RucchirawatXin Wei WangPublished in: Hepatology (Baltimore, Md.) (2022)
These results are consistent with the hypothesis that increased apoptotic cell death may lead to greater tumor heterogeneity and thus worse patient outcomes.