Depression and cognitive function in early multiple sclerosis: Multitasking is more sensitive than traditional assessments.

Lisa GlukhovskyDaniel KurzRachel BrandstadterVictoria M LeavittStephen KriegerMichelle FabianIlana Katz SandSylvia KlineovaClaire S RileyFred D LublinAaron E MillerJames F Sumowski

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

Depression symptoms are linked to cognitive multitasking in early MS; standard monotasking cognitive assessments appear less sensitive to depression-related cognition. Further investigation should determine directionality and mechanisms of this relationship, with the goal of enhancing treatment for cognitive dysfunction and depression in MS.

Keyphrases

multiple sclerosis
depressive symptoms
sleep quality
mass spectrometry
ms ms
white matter
physical activity
combination therapy