Esculetin Protects Human Retinal Pigment Epithelial Cells from Lipopolysaccharide-induced Inflammation and Cell Death.

S Altan OzalKader TurkekulVuslat GurluHande GucluSuat Erdogan

Published in: Current eye research (2018)

These results suggest that esculetin may be an alternative treatment option for endotoxin-induced inflammation and oxidative stress, which therefore may inhibit the development of LPS-mediated AMD.

Keyphrases

oxidative stress
lipopolysaccharide induced
diabetic rats
inflammatory response
cell death
endothelial cells
high glucose
dna damage
induced apoptosis
induced pluripotent stem cells
combination therapy
cell proliferation
cell cycle arrest
signaling pathway
heat shock protein
replacement therapy