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Proof of pharmacology of Org 48775-0, a p38 MAP kinase inhibitor, in healthy volunteers.

Matthijs MoerlandAndrea J KalesKaren BroekhuizenUlla NässanderRob NelissenMarieke L de KamPierre A M PeetersJacobus Burggraaf
Published in: British journal of clinical pharmacology (2020)
Org 48,775-0 has the capacity to significantly inhibit MAP kinase activity in humans without safety concerns.
Keyphrases
  • high density
  • protein kinase
  • tyrosine kinase