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Comparison Study of the Bio-Plex and Meso Scale Multiplexed SARS-CoV-2 Serology Assays Reveals Evidence of Diminished Host Antibody Responses to SARS-CoV-2 after Monoclonal Antibody Treatment.

Urvi M ParikhAmy L HeapsDaniela MoisiKelley C GordonJohn W MellorsManish C ChoudharyRinki DeoCarlee MoserPaul KlekotkaAlan L LandayJudith S CurrierJoseph J EronKara W ChewDavey M SmithJonathan Z LiScott F Siegnull null
Published in: Pathogens & immunity (2024)
These data demonstrate the utility in using multiplex immunoassays for characterizing the immune responses with and without treatment in a study population and provide evidence that monoclonal antibody treatment in acute COVID-19 may have a modest negative impact on development of host IgG responses.
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