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Quantitative Susceptibility Mapping of the Thalamus: Relationships with Thalamic Volume, Total Gray Matter Volume, and T2 Lesion Burden.

Gloria C ChiangJ HuEric D MorrisYi WangSusan A Gauthier
Published in: AJNR. American journal of neuroradiology (2018)
Iron levels in the thalami are associated with T2 lesion burden and the presence of enhancing lesions, but not with thalamic or gray matter volumes, suggesting that iron accumulation is associated with white matter inflammation rather than gray matter neurodegeneration.
Keyphrases
  • deep brain stimulation
  • white matter
  • high resolution
  • oxidative stress
  • iron deficiency
  • risk factors
  • multiple sclerosis
  • high density