Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells.

Tianke ZhangE DuYan LiuJun ChengZhihong ZhangYong XuShiyong QiYue Chen

Published in: International journal of nanomedicine (2020)

We reveal a novel epigenetic mechanism for anticancer effects of nZnO in bladder cancer cells under low-dose exposure. This study will provide experimental basis for the toxicology and cancer therapy of nanomaterials.

Keyphrases

oxide nanoparticles
dna methylation
low dose
cancer therapy
genome wide
induced apoptosis
drug delivery
cell cycle arrest
gene expression
spinal cord injury
high dose
single cell
cell death
endoplasmic reticulum stress
signaling pathway
urinary tract