IL-1β Impacts Vascular Integrity and Lymphatic Function in the Embryonic Omentum.
Matthew MenendezAnna DrozdKatarzyna BorawskaJoanna J ChmielewskaMeng-Ling WuCourtney T GriffinPublished in: Circulation research (2022)
in embryonic macrophages leads to excessive IL-1β production, erythrocyte leakage from blood vessels, and blood-filled lymphatics in the developing omentum. Altogether, these results highlight a novel context for epigenetically regulated crosstalk between macrophages, blood vessels, and lymphatics.