The chimeric HIV-1 Nef-Tat antigen was highly immunogenic, especially when applied in a heterologous prime/ boost regimen. This regimen could direct immune response toward cellular immunity (Th1 and CTL activity) and increase IFN-γ secretion after virus exposure.
Keyphrases
- immune response
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- dendritic cells
- cell therapy
- circulating tumor
- saccharomyces cerevisiae
- south africa
- cell free
- cancer therapy
- stem cells
- binding protein
- small molecule
- protein protein
- anti inflammatory