Genetically predicted circulating interleukin-18 levels are associated with risk of systemic lupus erythematosus and type 1 diabetes.

Wei-Zi QinXu-Fan WangRui LengWen-Jing XuFei-Fei WangWei ZhaoRui-Xue Leng

Published in: Lupus (2024)

Our analyses suggest that circulating IL-18 is significantly related to SLE and T1D and may serve as a potential target for the treatment of these diseases.

Keyphrases

systemic lupus erythematosus
type diabetes
disease activity
cardiovascular disease
rheumatoid arthritis
risk assessment
metabolic syndrome
adipose tissue
human health
replacement therapy
weight loss
skeletal muscle
drug induced