Microporous Triptycene-Based Affinity Materials on Quartz Crystal Microbalances for Tracing of Illicit Compounds.

Triptycene-based organic molecules of intrinsic microporosity (OMIMs) with extended functionalized π-surfaces are excellent materials for gas sorption and separation. In this study, the affinities of triptycene-based OMIM affinity materials on 195 MHz high-fundamental-frequency quartz crystal microbalances (HFF-QCMs) for hazardous and illicit compounds such as piperonal and (-)-norephedrine were determined. Both new and existing porous triptycene-based affinity materials were investigated, resulting in very high sensitivities and selectivities that could be applied for sensing purposes. Remarkable results were found for safrole - a starting material for illicit compounds such as ecstasy. A systematic approach highlights the effects of different size of π-surfaces of these affinity materials, allowing a classification of the properties that might be optimal for the design of future OMIM-based affinity materials.