Cell-free DNA testing of maternal blood in screening for trisomies in twin pregnancy: updated cohort study at 10-14 weeks and meta-analysis.

H JudahMaría Del Mar Gil Argyro SyngelakiS GalevaJacques C Jani Ranjit AkolekarK H Nicolaides

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)

In twin pregnancy, the reported DR of trisomy 21 by cfDNA testing is high, but lower than that in singleton pregnancy, whereas the FPR appears to be equally low. The number of cases of trisomy 18 and more so trisomy 13 was too small for accurate assessment of the predictive performance of the cfDNA test. © 2021 International Society of Ultrasound in Obstetrics and Gynecology.

Keyphrases

preterm birth
pregnancy outcomes
magnetic resonance imaging
birth weight
pregnant women
high resolution
weight loss
editorial comment