Increased Prevalence of Moderate to Severe Mitral and Aortic Valve Dysfunction in Systemic Sclerosis: A Case-control Study.
Francisco Javier NarváezJudit LLuchAlejandro Ruiz-MajoralMiguel Angel Sánchez-CorralEduard ClaverJoan Miquel NollaPublished in: The Journal of rheumatology (2020)
We found an increased prevalence of moderate to severe MR and AS in SSc compared to age-matched non-SSc controls with similar CV comorbidities. While results from this study do not allow for establishing a direct causal relationship, they strongly support the contribution of SSc-specific factors in the development of these complications.
Keyphrases
- systemic sclerosis
- aortic valve
- aortic stenosis
- risk factors
- interstitial lung disease
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- high intensity
- early onset
- mitral valve
- oxidative stress
- magnetic resonance
- ejection fraction
- magnetic resonance imaging
- rheumatoid arthritis
- left atrial
- coronary artery disease