National trends in hospitalizations among patients with colorectal cancer in the United States.

Colorectal cancer is the second leading cause of cancer-related death in the United States, with a rising incidence, especially in young adults. Care for patients with colorectal cancer is associated with significant healthcare costs and expenditures. We retrospectively interrogated the National Inpatient Sample for admissions in patients with colorectal cancer from 2007 to 2017. A total of 1,962,705 admissions were identified: 50.2% were men, 64.4% were white, and the median age was 68. Most admissions (47.8%) that were coded for anatomical location of malignancy were for ascending colon cancer. The average in-hospital mortality was 4.9%, with a lower mortality in admissions with ascending colon cancer (2.9, P  < 0.001). The median length of stay was 5 days, with a longer stay in admissions with transverse colon cancer (9 days, P  < 0.0001). The median cost of hospitalization was $12,295 and was significantly higher for patients with descending colon malignancy ($16,369, P  < 0.0001). The number of annual hospitalizations stayed steady overall but increased by 98.6% for rectosigmoid cancer. Our findings highlight the high costs of hospitalization and the overall economic burden associated with inpatient admissions among patients with colorectal cancer.