Transcatheter Arterial Embolization Containing Donafenib Induces Anti-Angiogenesis and Tumoricidal CD8+ T-Cell Infiltration in Rabbit VX2 Liver Tumor.

Qin ShiTongqiang LiSongjiang HuangYaowei BaiYingliang WangJiacheng LiuChen ZhouYang ChenBin Xiong

Published in: Cancer management and research (2021)

The combination of TAE and angiogenesis inhibitor donafenib resulted in a potentiated tumoricidal effect, anti-angiogenesis and antitumour T cell response in rabbit VX2 liver tumor model. This may provide a potential basis for exploring the immune-related mechanisms of embolization in liver cancer.

Keyphrases

endothelial cells
vascular endothelial growth factor
wound healing
climate change